Brain imaging GWAS Data Interactive PheWeb server: 33k subjects (discovery+replication pooled) and 22k subjects (discovery only)
English
United Kingdom, Oxford
Oxford University

数据描述

Brain imaging GWAS Data Interactive PheWeb server: 33k subjects (discovery+replication pooled) and 22k subjects (discovery only)

The Oxford Brain Imaging Genetics Server (BIG40) is an open GWAS results dataset linking genetic variation to brain imaging-derived phenotypes (IDPs) from the UK Biobank multimodal imaging release (~40,000 participants, early 2020). It provides association summary statistics for ~4,000 IDPs and QC measures (including derived connectivity features), based on a discovery cohort of 22,138 subjects, a replication cohort of 11,086, and a combined ~33k-sample analysis. The resource covers chromosomes 1–22 and X, reporting results for 17,103,079 SNPs on GRCh37/hg19, and includes variant annotations, per-IDP sample sizes (including X pseudoautosomal/non-pseudoautosomal strata), heritability estimates, and peak association tables to support brain imaging genetics discovery and replication.

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