ABCD Study
English
United States, Austin
Hospital Los Angeles Florida International University Laureate Institute for Brain Research
数据描述
No dataset description found.
abcdstudy.org
IP: 141.193.213.10
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相关论文
54Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence
Xinran Wu•Kai Zhang•Nanyu Kuang•Xiangzhen Kong•Miao Cao等 18 人
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2025
•2025/5/14
•Vol.16 No.1 p.1-15
Cerebral asymmetry, fundamental to various cognitive functions, is often disrupted in neuropsychiatric disorders. While brain growth has been extensively studied, the maturation of brain asymmetry in children and the factors influencing it in adolescence remain poorly understood. We analyze lon...
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Hormonal contraceptive intake during adolescence and cortical brain measures in the ABCD Study
Carina Heller•Elvisha Dhamala•Katherine L. Bottenhorn•Megan M. Herting•Brian Bossé等 10 人
Npj Women's Health
2025
•2025/9/22
•Vol.3 No.1 p.1-9
Adolescence is a critical period for brain development, shaped in part by rising levels of sex steroids. During this time, some females initiate the use of hormonal contraception (HC), which suppresses endogenous ovarian hormone production. Using data from the ABCD Study’s four-year follow-up (avera...
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Network temperature as a metric of stability in depression symptoms across adolescence
Poppy Z. Grimes•Aja L. Murray•Keith Smith•Andrea G. Allegrini•Giulia G. Piazza等 9 人
Nature Mental Health
2025
•2025/4/29
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Depression is characterized by diverse symptom combinations that can be represented as dynamic networks. While previous research has focused on central symptoms for targeted interventions, less attention has been given to whole-network properties. Here we show that ‘network temperature’, a novel mea...
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Social epidemiology of the Mediterranean-dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet among early adolescents: the adolescent brain cognitive development study
Jason M. Nagata•Ammal Bashir•Shayna Weinstein•Abubakr A. A. Al-Shoaibi•Iris Yuefan Shao等 8 人
Pediatric Research
2023
•2023/12/15
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The purpose of our study was to understand the relationship between sociodemographic factors and adherence to the MIND (Mediterranean-DASH [Dietary Approaches to Stop Hypertension] Intervention for Neurodegenerative Delay) diet in a demographically diverse national population-based sample of 9–12-ye...
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Early pubertal timing is a risk factor for adolescent dysmenorrhea
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Npj Women's Health
2025
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Females who experience menarche early have elevated risk for dysmenorrhea; yet, other puberty features precede menarche. Using data from the Adolescent Brain Cognitive Development Study®, pubertal timing was estimated via random effects linear growth curves of pubertal status indicators excluding me...
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Nature Mental Health
2024
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Etiologic insights into psychopathology may be gained by using hypothesis-free methods to identify associations between genetic risk for broad psychopathology and phenotypes measured during adolescence, including both markers of child psychopathology and intermediate phenotypes such as neural struct...
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Yi-Jun Ge•Bang-Sheng Wu•Yi Zhang•Shi-Dong Chen•Ya-Ru Zhang等 43 人
Nature Human Behaviour
2023
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The cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here we aggregated genetic and neuroimaging data from 61,974 participants (age range, 9 to 98 ye...
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Deviation in development of dorsal association tracts during preadolescence links to concurrent and future cognitive performance and transdiagnostic psychopathology
Danni Wang•Christopher J. Hammond•Betty Jo Salmeron•Xiang Xiao•Laura Murray等 14 人
Nature Communications
2026
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Many psychiatric disorders begin during adolescence, coinciding with the rapid development of brain white matter (WM). However, it remains unclear whether deviations from normal WM development during this period contribute to psychopathology. In this study, we developed normative models of brain age...
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Socioeconomic status, BMI, and brain development in children
Dennis Evan•Manza Peter•Volkow Nora D.
Translational Psychiatry
2022
•2022/1/24
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Low socioeconomic status (SES) in childhood is associated with deficits in executive function and changes in cortical morphology. Furthermore, rates of childhood obesity are greater among low SES children and childhood obesity is also associated with cortical alterations and impaired neurocognition,...
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10.1038/S41398-022-01779-3
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Cognitive and global morphometry trajectories as predictors of persistent distressing psychotic-like experiences in youth
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Psychotic-like experiences (PLEs) may result from genetic and environmental risk factors that contribute to progressive declines in cognition and brain morphometry, which in turn exacerbate PLEs over time. Here we used three waves of unique longitudinal Adolescent Brain Cognitive Development Study d...
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10.1038/S44220-025-00481-9
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Sleep moderates how prenatal and childhood pollutant exposure impacts white matter microstructural integrity in adolescence
Devyn L. Cotter•Orsolya Kiss•Hedyeh Ahmadi•Alethea V. de Jesus•Joel Schwartz等 8 人
Npj Biological Timing And Sleep
2025
•2025/11/4
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Air pollution is a ubiquitous neurotoxicant linked to altered structural brain connectivity. Sleep may offer neuroprotection through its roles in brain waste clearance and immune regulation. Using Fitbit-derived sleep data and multi-shell diffusion MRI from 2178 children (ages 10–13) in the ABCD Stu...
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Investigating grey matter volumetric trajectories through the lifespan at the individual level
Runye Shi•Shitong Xiang•Tianye Jia•Trevor W. Robbins•Jujiao Kang等 33 人
Nature Communications
2024
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Adolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the neurobiological basis underlying individual heterogeneity rem...
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Population-level normative models reveal race- and socioeconomic-related variability in cortical thickness of threat neurocircuitry
Nathaniel G. Harnett•Negar Fani•Grace Rowland•Poornima Kumar•Saige Rutherford等 6 人
Communications Biology
2024
•2024/6/19
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The inequitable distribution of economic resources and exposure to adversity between racial groups contributes to mental health disparities within the United States. Consideration of the potential neurodevelopmental consequences, however, has been limited particularly for neurocircuitry known to reg...
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Jonatan Ottino González•Miguel Angel Rivas Fernández•Sevan Esaian•Vidya Rajagopalan•Mustapha Bouhrara等 7 人
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•2024/7/4
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Prenatal cannabis exposure (PCE) is associated with mental health problems in early adolescence, but the possible neurobiological mechanisms remain unknown. In a large longitudinal sample of adolescents (ages 9–12 years, n = 9,322–10,186), we find that PCE is associated with localized differences in...
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Arielle S. Keller•Adam R. Pines•Sheila Shanmugan•Valerie J. Sydnor•Zaixu Cui等 25 人
Nature Communications
2023
•2023/12/18
•Vol.14 No.1 p.1-14
Individual differences in cognition during childhood are associated with important social, physical, and mental health outcomes in adolescence and adulthood. Given that cortical surface arealization during development reflects the brain’s functional prioritization, quantifying variation in the topog...
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Chao Xie•Shitong Xiang•Yueyuan Zheng•Chun Shen•Yuzhu Li等 57 人
Nature Mental Health
2026
•2026/2/13
•Vol.4 No.3 p.362-376
Mounting evidence suggests that hierarchical psychopathology factors underlie psychiatric comorbidity. However, the exact neurobiological characterizations of these multilevel factors remain elusive. Here, leveraging the brain-behavior predictive framework with a 10-year longitudinal imaging-genetic...
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10.1038/S44220-025-00577-2
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The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders
Ya-Nan Ou•Yi-Jun Ge•Bang-Sheng Wu•Yi Zhang•Yu-Chao Jiang等 11 人
Translational Psychiatry
2023
•2023/5/26
•Vol.13 No.1 p.1-12
The fornix is a white matter bundle located in the center of the hippocampaldiencephalic limbic circuit that controls memory and executive functions, yet its genetic architectures and involvement in brain disorders remain largely unknown. We carried out a genome-wide association analysis of 30,832 U...
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10.1038/S41398-023-02475-6
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Data leakage inflates prediction performance in connectome-based machine learning models
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Nature Communications
2024
•2024/2/28
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Predictive modeling is a central technique in neuroimaging to identify brain-behavior relationships and test their generalizability to unseen data. However, data leakage undermines the validity of predictive models by breaching the separation between training and test data. Leakage is always an inco...
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Shu-Yi Huang•Yi-Jun Ge•Peng Ren•Bang-Sheng Wu•Weikang Gong等 20 人
Nature Communications
2025
•2025/1/13
•Vol.16 No.1 p.1-17
Brain glymphatic activity, as indicated by diffusion-tensor imaging analysis along the perivascular space (ALPS) index, is involved in developmental neuropsychiatric and neurodegenerative diseases, but its genetic architecture is poorly understood. Here, we identified 17 unique genome-wide significa...
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This study aimed to assess the independent and joint associations of genomic and exposomic liabilities for schizophrenia with distressing psychotic experiences (PEs) and their persistence in early adolescence. The Adolescent Brain and Cognitive Development Study data from children with European ance...
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Zhao Bingxin•Li Tengfei•Smith Stephen M.•Xiong Di•Wang Xifeng等 20 人
Nature Genetics
2022
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The human brain forms functional networks of correlated activity, which have been linked with both cognitive and clinical outcomes. However, the genetic variants affecting brain function are largely unknown. Here, we used resting-state functional magnetic resonance images from 47,276 individuals to ...
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Jason M. Nagata•Sana Alsamman•Natalia Smith•Jiayue Yu•Kyle T. Ganson等 9 人
Pediatric Research
2023
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Sociodemographic disparities in adolescent physical activity have been documented but mostly rely on self-reported data. Our objective was to examine differences in device-based step metrics, including daily step count (steps d−1), by sociodemographic factors among a diverse sample of 10-to-14-year-...
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10.1038/S41390-023-02700-4
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Kevin W. Hoffman•Kate T. Tran•Tyler M. Moore•Mārtiņš M. Gataviņš•Elina Visoki等 13 人
Nature Mental Health
2024
•2024/5/14
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Allostatic load (AL) is the cumulative ‘wear and tear’ on the body due to chronic adversity. We tested the poly-environmental (exposomic) and polygenic contributions to AL and their combined contribution to adolescent mental health. In this cohort study of N = 5,036 diverse youth (mean age 12 years)...
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10.1038/S44220-024-00255-9
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Fan Chun Chieh•Loughnan Robert•Makowski Carolina•Pecheva Diliana•Chen Chi-Hua等 12 人
Nature Communications
2022
•2022/5/3
•Vol.13 No.1 p.1-10
The molecular determinants of tissue composition of the human brain remain largely unknown. Recent genome-wide association studies (GWAS) on this topic have had limited success due to methodological constraints. Here, we apply advanced whole-brain analyses on multi-shell diffusion imaging data and m...
BrainGenetics of the nervous systemGenome-wide association studies
10.1038/S41467-022-30110-3
ISSN:2041-1723
Study design features increase replicability in brain-wide association studies
Kaidi Kang•Jakob Seidlitz•Richard A. I. Bethlehem•Jiangmei Xiong•Megan T. Jones等 19 人
Nature
2024
•2024/11/27
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Brain-wide association studies (BWAS) are a fundamental tool in discovering brain–behaviour associations1,2. Several recent studies have shown that thousands of study participants are required for good replicability of BWAS1–3. Here we performed analyses and meta-analyses of a robust effect size ind...
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10.1038/S41586-024-08260-9
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Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder
Louisa Schilling•S. Parker Singleton•Ceren Tozlu•Marie Hédo•Qingyu Zhao等 8 人
Nature Mental Health
2025
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An individual’s risk of substance use disorder (SUD) is shaped by potent biosocial factors. Family history is one of the strongest predictors, yet its impact on the brain before substance exposure remains unclear. Here we apply network control theory to estimate transition energies (TEs)—the input r...
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10.1038/S44220-025-00523-2
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Leon Qi Rong Ooi•Csaba Orban•Shaoshi Zhang•Thomas E. Nichols•Trevor Wei Kiat Tan等 28 人
Nature
2025
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A pervasive dilemma in brain-wide association studies1 (BWAS) is whether to prioritize functional magnetic resonance imaging (fMRI) scan time or sample size. We derive a theoretical model showing that individual-level phenotypic prediction accuracy increases with sample size and total scan duration ...
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10.1038/S41586-025-09250-1
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The genetic architecture of human amygdala volumes and their overlap with common brain disorders
Ou Ya-Nan•Wu Bang-Sheng•Ge Yi-Jun•Zhang Yi•Jiang Yu-Chao等 11 人
Translational Psychiatry
2023
•2023/3/11
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The amygdala is a crucial interconnecting structure in the brain that performs several regulatory functions, yet its genetic architectures and involvement in brain disorders remain largely unknown. We carried out the first multivariate genome-wide association study (GWAS) of amygdala subfield volume...
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10.1038/S41398-023-02387-5
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Cognitive and psychiatric relevance of dynamic functional connectivity states in a large (N > 10,000) children population
Zening Fu•Jing Sui•Armin Iraji•Jingyu Liu•Vince D. Calhoun
Molecular Psychiatry
2024
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Children’s brains dynamically adapt to the stimuli from the internal state and the external environment, allowing for changes in cognitive and mental behavior. In this work, we performed a large-scale analysis of dynamic functional connectivity (DFC) in children aged 9~11 years, investigating how br...
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10.1038/S41380-024-02683-6
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Breastfeeding duration and brain-body development in 9–10-year-olds: modulating effect of socioeconomic levels
Vidya Rajagopalan•Eustace Hsu•Shan Luo
Pediatric Research
2024
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To investigate relationships of breastfeeding duration with brain structure and adiposity markers in youth and how these relationships are modified by neighborhood socioeconomic environments (SEEs). This was a cross-sectional study of youth enrolled in the Adolescent Brain and Cognitive Development ...
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10.1038/S41390-024-03330-0
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Interplay of socioeconomic status, cognition, and school performance in the ABCD sample
Lara Langensee•Theodor Rumetshofer•Johan Mårtensson
Npj Science Of Learning
2024
•2024/3/11
•Vol.9 No.1 p.1-8
Coming from a disadvantaged background can have negative impact on an individual’s educational trajectory. Some people however seem unaffected and cope well with the demands and challenges posed by school education, despite growing up in adverse conditions, a phenomenon termed academic resilience. W...
EducationHuman behaviour
10.1038/S41539-024-00233-X
ISSN:2056-7936
Nonergodicity and Simpson’s paradox in neurocognitive dynamics of cognitive control
Percy K. Mistry•Nicholas K. Branigan•Zhiyao Gao•Weidong Cai•Vinod Menon
Nature Communications
2026
•2026/4/27
•Vol.17 No.1 p.34940
Nonergodicity and Simpson’s paradox present significant, yet underappreciated challenges in cognitive neuroscience. Leveraging brain imaging and behavioral data from over 4000 individuals and a Bayesian computational model of cognitive dynamics, we investigated brain-behavior relationships underlyin...
Cognitive controlComputational neuroscienceHuman behaviour
10.1038/S41467-026-71404-0
ISSN:2041-1723
Estimating the total variance explained by whole-brain imaging for zero-inflated outcomes
Junting Ren•Robert Loughnan•Bohan Xu•Wesley K. Thompson•Chun Chieh Fan
Communications Biology
2024
•2024/7/9
•Vol.7 No.1 p.1-12
There is a dearth of statistical models that adequately capture the total signal attributed to whole-brain imaging features. The total signal is often widely distributed across the brain, with individual imaging features exhibiting small effect sizes for predicting neurobehavioral phenotypes. The ch...
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10.1038/S42003-024-06504-Y
ISSN:2399-3642
Latent space-based network analysis for brain–behavior linking in neuroimaging
Selena Wang•Xinzhi Zhang•Yunhe Liu•Wanwan Xu•Xinyuan Tian等 6 人
Nature Methods
2025
•2025/12/4
•00 p.1-11
We propose a latent space-based statistical network analysis (LatentSNA) method that implements network science in a generative Bayesian framework, preserves neurologically meaningful brain topology and improves statistical power for imaging biomarker detection. LatentSNA (1) addresses the lack of p...
Network topologyStatistical methods
10.1038/S41592-025-02896-9
ISSN:1548-7091
Neuroanatomy reflects individual variability in impulsivity in youth
Elvisha Dhamala•Erynn Christensen•Jamie L. Hanson•Jocelyn A. Ricard•Noelle Arcaro等 11 人
Molecular Psychiatry
2026
•2026/3/24
•00 p.1-15
Individual differences in neural circuits underlying emotional regulation, motivation, and decision-making are implicated in many psychiatric illnesses. Interindividual variability in these circuits may manifest, at least in part, as individual differences in impulsivity. Impulsivity reflects a tend...
Biological techniquesNeurosciencePsychiatric disorders
10.1038/S41380-026-03526-2
ISSN:1359-4184
Regularized CCA identifies sex-specific brain-behavior associations in adolescent psychopathology
Leo Milecki•Camila Gonzalez•Ehsan Adeli•Kate B. Nooner•Mert R. Sabuncu等 7 人
Translational Psychiatry
2025
•2025/10/17
•Vol.15 No.1 p.1-10
Adolescence is a critical period of neural development and a sensitive window for the emergence of psychiatric symptoms. Resting-state functional MRI (rs-fMRI) provides a unique opportunity to investigate brain-behavior associations. However, the role of sex-specific differences in these association...
Human behaviourNeuroscience
10.1038/S41398-025-03678-9
ISSN:2158-3188
Distinct brain network features predict internalizing and externalizing traits in children, adolescents and adults
Yueyue Lydia Qu•Jianzhong Chen•Angela Tam•Leon Qi Rong Ooi•Elvisha Dhamala等 11 人
Nature Mental Health
2025
•2025/2/19
•Vol.3 No.3 p.306-317
The distinction between externalizing and internalizing traits has been a classic area of study in psychiatry. However, whether shared or unique brain network features predict internalizing and externalizing behaviors remains poorly understood. Using a sample of 5,260 children from the Adolescent Br...
Cognitive neurosciencePsychology
10.1038/S44220-025-00388-5
ISSN:2731-6076
A pattern-learning algorithm associates copy number variations with brain structure and behavioural variables in an adolescent population cohort
Jakub Kopal•Guillaume Huguet•Justin Marotta•Shambhavi Aggarwal•Nicole Osayande等 16 人
Nature Biomedical Engineering
2025
•2025/7/18
•00 p.1-16
Our genetic makeup, together with environmental and social influences, shape our brain’s development. Yet, the imaging-genetics field has struggled to integrate all these modalities to investigate the interplay between genetic blueprint, brain architecture, environment, human health and daily living...
NeuroscienceQuality of lifeRare variants
10.1038/S41551-025-01454-0
ISSN:2157-846X
Social epidemiology of early adolescent problematic screen use in the United States
Nagata Jason M.•Singh Gurbinder•Sajjad Omar M.•Ganson Kyle T.•Testa Alexander等 10 人
Pediatric Research
2022
•2022/6/29
•Vol.92 No.5 p.1443-1449
To determine sociodemographic correlates of problematic screen use (social media, video games, mobile phones) among a racially/ethnically and socioeconomically diverse population-based sample of 10–14-year-old early adolescents. We analyzed cross-sectional data from the Adolescent Brain Cognitive De...
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10.1038/S41390-022-02176-8
ISSN:0031-3998
Characterizing the co-occurrence of alcohol experimentation and suicidal thoughts and behaviors in early adolescence
Séverine Lannoy•James M. Bjork•Mallory Stephenson•Sandra Sanchez-Roige•Kristin Passero等 6 人
Translational Psychiatry
2026
•2026/1/30
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This study aims to investigate the roles of decision-making processes and genetics in the co-occurrence of alcohol use and suicidal thoughts/behaviors (STB) in adolescence. We used data from the ABCD® study (abcdstudy.org) and included behavioral (computerized tasks, self-report questionnaires) and ...
GeneticsHuman behaviour
10.1038/S41398-026-03826-9
ISSN:2158-3188
Macroeconomic income inequality, brain structure and function, and mental health
Divyangana Rakesh•Dimitris I. Tsomokos•Teresa Vargas•Kate E. Pickett•Vikram Patel
Nature Mental Health
2025
•2025/9/30
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Income inequality, a structural property of societies characterized by the unequal distribution of resources, is associated with adverse mental health outcomes during adolescence, which is a sensitive period of neurodevelopment. While previous research has explored the impact of individual-level soc...
Cognitive neuroscienceInterdisciplinary studiesPsychologyStress and resilience
10.1038/S44220-025-00508-1
ISSN:2731-6076
Social epidemiology of early adolescent nutrition
Jason M. Nagata•Christiane K. Helmer•Jennifer Wong•Thang Diep•Sydnie K. Domingue等 14 人
Pediatric Research
2025
•2025/1/27
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This study aimed to investigate associations between sociodemographic factors and dietary intake among a diverse population of early adolescents ages 10–13 years in the United States. We examined data from the Adolescent Brain Cognitive Development (ABCD) Study in Year 2 (2018–2020, ages 10–13 years...
Medicine/Public Health, generalPediatricsPediatric Surgery
10.1038/S41390-025-03838-Z
ISSN:0031-3998
Neural correlates differ between crystallized and fluid intelligence in adolescents
Bowen Qiu•Rui Qian•Baorong Gu•Zichao Li•Zhifan Chen等 15 人
Translational Psychiatry
2025
•2025/7/17
•Vol.15 No.1 p.1-12
Fluid and crystallized intelligence are acknowledged as distinct facets of cognitive ability during brain development, but the specific neural substrates and molecular mechanisms underlying them remain unclear. This study used a sample comprising 7471 young adolescents (mean age 9.87 ± 0.62 years) f...
NeurosciencePredictive markers
10.1038/S41398-025-03467-4
ISSN:2158-3188
Social epidemiology of sports and extracurricular activities in early adolescents
Jason M. Nagata•Jennifer H. Wong•Christiane K. Helmer•Thang Diep•Sydnie K. Domingue等 12 人
Pediatric Research
2025
•2025/5/4
•00 p.1-10
This study examines the social epidemiology of sports and extracurricular activities in early adolescents (9–14 years) using a diverse national U.S. sample. We examined data from baseline (2016–2018, ages 9–10) to Year 3 follow-up (2019–2021) of the Adolescent Brain and Cognitive Development (ABCD) ...
Medicine/Public Health, generalPediatricsPediatric Surgery
10.1038/S41390-025-04099-6
ISSN:0031-3998
Associations between media parenting practices and early adolescent screen use
Jason M. Nagata•Angel Paul•Felicia Yen•Zacariah Smith-Russack•Iris Yuefan Shao等 11 人
Pediatric Research
2024
•2024/6/5
•00 p.1-8
To assess the prevalence of various media parenting practices and identify their associations with early adolescent screen time and problematic social media, video game, and mobile phone use. Cross-sectional data from Year 3 of the Adolescent Brain Cognitive Development (ABCD) Study (2019–2022) that...
Medicine/Public Health, generalPediatricsPediatric Surgery
10.1038/S41390-024-03243-Y
ISSN:0031-3998
Genetic liability to major psychiatric disorders contributes to multi-faceted quality of life outcomes in children and adults
Yingjie Shi•Nina Roth Mota•Barbara Franke•Emma Sprooten
Translational Psychiatry
2025
•2025/7/7
•Vol.15 No.1 p.1-8
Psychiatric conditions, known for their hereditary nature, exert significant impacts on various life domains. Leveraging this heritability, we examine the relations between genetic susceptibility to major psychiatric disorders and the multifaceted aspects of quality of life in two population-based c...
GenomicsPsychiatric disorders
10.1038/S41398-025-03443-Y
ISSN:2158-3188
A shared neural basis underlying psychiatric comorbidity
Xie Chao•Xiang Shitong•Shen Chun•Peng Xuerui•Kang Jujiao等 35 人
Nature Medicine
2023
•2023/4/24
•00 p.1-11
Recent studies proposed a general psychopathology factor underlying common comorbidities among psychiatric disorders. However, its neurobiological mechanisms and generalizability remain elusive. In this study, we used a large longitudinal neuroimaging cohort from adolescence to young adulthood (IMAG...
Cognitive controlPsychiatric disorders
10.1038/S41591-023-02317-4
ISSN:1078-8956
Social epidemiology of gender diversity in early adolescents
Jason M. Nagata•Karen Li•Shirley S. Sui•Patrick Low•Jonanne Talebloo等 13 人
Pediatric Research
2025
•2025/11/26
•00 p.1-8
Few large U.S. cohort studies have examined multidimensional measures of gender diversity; therefore, this study investigates their associations with sociodemographic factors in a national sample of 12- to 13-year-old adolescents. We conducted a cross-sectional analysis of Adolescent Brain Cognitive...
Medicine/Public Health, generalPediatricsPediatric Surgery
10.1038/S41390-025-04576-Y
ISSN:0031-3998
Association between vmPFC gray matter volume and smoking initiation in adolescents
Shitong Xiang•Tianye Jia•Chao Xie•Wei Cheng•Bader Chaarani等 30 人
Nature Communications
2023
•2023/8/15
•Vol.14 No.1 p.1-13
Smoking of cigarettes among young adolescents is a pressing public health issue. However, the neural mechanisms underlying smoking initiation and sustenance during adolescence, especially the potential causal interactions between altered brain development and smoking behaviour, remain elusive. Here,...
AddictionCognitive neuroscienceGenetics of the nervous systemPredictive markers
10.1038/S41467-023-40079-2
ISSN:2041-1723
Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
E. P. Tissink•A. A. Shadrin•D. van der Meer•N. Parker•G. Hindley等 18 人
Nature Communications
2024
•2024/3/26
•Vol.15 No.1 p.1-13
Genetic pleiotropy is abundant across spatially distributed brain characteristics derived from one neuroimaging modality (e.g. structural, functional or diffusion magnetic resonance imaging [MRI]). A better understanding of pleiotropy across modalities could inform us on the integration of brain fun...
Genetics of the nervous systemGenome-wide association studies
10.1038/S41467-024-46817-4
ISSN:2041-1723
Prospective associations of sleep duration and screen time with transition from overweight/obesity to normal BMI in U.S. adolescents
Abubakr A. Al-Shoaibi•Christiane K. Helmer•Kyle T. Ganson•Alexander Testa•Jason M. Lavender等 10 人
International Journal Of Obesity
2025
•2025/12/23
•00 p.1-8
Shorter sleep duration and longer screen time are established risk factors for adolescent obesity. However, the extent to which these behaviors are prospectively associated with the transition back from overweight/obesity to a healthy status remains unclear. We examined whether sleep duration and sc...
EpidemiologyRisk factors
10.1038/S41366-025-01980-6
ISSN:0307-0565