Gene Expression Clustering
English
United States, Chicago
GDC

数据描述

Gene Expression Clustering

The dataset contains clinical data for 25,269 cases, including gene expression data for 20,712 cases, somatic mutation data for 18,640 cases, and data related to protein mutations for 16,508 cases. It includes cohort-level mutation frequency data for 17,771 cases. The data is part of Data Release 41.0 and is considered provisional due to evolving analysis pipelines.

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相关论文

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Prediction of brain metastasis development with DNA methylation signatures

Jeffrey A. ZuccatoYasin MamatjanFarshad NassiriAndrew AjisebutuJeffrey C. Liu21
Nature Medicine
2024
2024/10/8
00 p.1-10
Brain metastases (BMs) are the most common and among the deadliest brain tumors. Currently, there are no reliable predictors of BM development from primary cancer, which limits early intervention. Lung adenocarcinoma (LUAD) is the most common BM source and here we obtained 402 tumor and plasma sampl...
CNS cancerDiagnostic markersMethylation analysisNon-small-cell lung cancerPredictive markers
10.1038/S41591-024-03286-Y
ISSN:1078-8956

AI-based histopathology image analysis reveals a distinct subset of endometrial cancers

Amirali DarbandsariHossein FarahaniMaryam AsadiMatthew WiensDawn Cochrane20
Nature Communications
2024
2024/6/26
Vol.15 No.1 p.1-12
Endometrial cancer (EC) has four molecular subtypes with strong prognostic value and therapeutic implications. The most common subtype (NSMP; No Specific Molecular Profile) is assigned after exclusion of the defining features of the other three molecular subtypes and includes patients with heterogen...
Cancer genomicsCancer imagingEndometrial cancerMachine learningPrognostic markers
10.1038/S41467-024-49017-2
ISSN:2041-1723

KiGEP: a quantitative algorithm for calculating human kidney similarity and nephrotoxicity in human kidney organoids

Sugi LeeHyun Mi KangJung Hwa LimDae Hun KimKunhyang Park10
Experimental & Molecular Medicine
2026
2026/8/3
00 p.1-10
Kidney organoids (KOs) are being actively developed and used as models for evaluating nephrotoxicity, which is an important process during drug development. To evaluate human pluripotent stem cell-derived KOs, various lineage markers have been used to confirm KO differentiation via quantitative real...
DifferentiationEmbryonic germ cellsInduced pluripotent stem cells
10.1038/S12276-026-01785-1
ISSN:2092-6413