Risk/Outcome pairs with their respective risk-outcome scores and star ratings
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Risk/Outcome pairs with their respective risk-outcome scores and star ratings

This dataset presents risk/outcome pairs, including factors like high fasting plasma glucose and smoking, linked to health outcomes such as chronic kidney disease and larynx cancer. It includes risk-outcome scores, star ratings representing robustness of results, and data types for each pair. The dataset encompasses 154 risk/outcome pairs, providing an overview of associations and strength of evidence for each.

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相关论文

11

The Burden of Proof studies: assessing the evidence of risk

Zheng PengAfshin AshkanBiryukov StanBisignano CatherineBrauer Michael43
Nature Medicine
2022
2022/10/10
Vol.28 No.10 p.2038-2044
Exposure to risks throughout life results in a wide variety of outcomes. Objectively judging the relative impact of these risks on personal and population health is fundamental to individual survival and societal prosperity. Existing mechanisms to quantify and rank the magnitude of these myriad effe...
DiseasesRisk factors
10.1038/S41591-022-01973-2
ISSN:1078-8956

Health effects associated with consumption of unprocessed red meat: a Burden of Proof study

Lescinsky HaleyAfshin AshkanAshbaugh CharlieBisignano CatherineBrauer Michael18
Nature Medicine
2022
2022/10/10
Vol.28 No.10 p.2075-2082
Characterizing the potential health effects of exposure to risk factors such as red meat consumption is essential to inform health policy and practice. Previous meta-analyses evaluating the effects of red meat intake have generated mixed findings and do not formally assess evidence strength. Here, w...
CancerCardiovascular diseasesRisk factors
10.1038/S41591-022-01968-Z
ISSN:1078-8956

Maternal and neonatal outcomes associated with haemoglobin concentration in pregnancy: a Burden of Proof study

Ni Gusti Ayu NandithaDong Keun RheeCorey J. TeplyHeidi A. TandionoIhunaya Okorie32
Nature Health
2026
2026/6/24
00 p.1-14
This study evaluated dose–response relationships between haemoglobin concentration in pregnancy and maternal and neonatal outcomes based on comprehensive systematic reviews using the Burden of Proof meta-analytic framework. Risk estimates accounting for uncertainty and quantitative star ratings were...
EpidemiologyRisk factors
10.1038/S44360-026-00129-7
ISSN:3005-0693

Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study

Razo ChristianWelgan Catherine A.Johnson Catherine O.McLaughlin Susan A.Iannucci Vincent15
Nature Medicine
2022
2022/10/10
Vol.28 No.10 p.2056-2065
High systolic blood pressure (SBP) is a major risk factor for ischemic heart disease (IHD), the leading cause of death worldwide. Using data from published observational studies and controlled trials, we estimated the mean SBP–IHD dose–response function and burden of proof risk function (BPRF), and ...
Cardiovascular diseasesRisk factors
10.1038/S41591-022-01974-1
ISSN:1078-8956

Health effects associated with exposure to intimate partner violence against women and childhood sexual abuse: a burden of proof study

Cory N. SpencerMariam KhalilMolly HerbertAleksandr Y. AravkinAlejandra Arrieta38
Nature Medicine
2023
2023/12/11
00 p.1-16
The health impacts of intimate partner violence against women and childhood sexual abuse are not fully understood. Here we conducted a systematic review by comprehensively searching seven electronic databases for literature on intimate partner violence-associated and childhood sexual abuse-associate...
Risk factorsTrauma
10.1038/S41591-023-02629-5
ISSN:1078-8956

Health effects associated with exposure to secondhand smoke: a Burden of Proof study

Luisa S. FlorJason A. AndersonNoah AhmadAleksandr AravkinSinclair Carr18
Nature Medicine
2024
2024/1/9
00 p.1-19
Despite a gradual decline in smoking rates over time, exposure to secondhand smoke (SHS) continues to cause harm to nonsmokers, who are disproportionately children and women living in low- and middle-income countries. We comprehensively reviewed the literature published by July 2022 concerning the a...
DiseasesRisk factors
10.1038/S41591-023-02743-4
ISSN:1078-8956

Health effects associated with consumption of processed meat, sugar-sweetened beverages and trans fatty acids: a Burden of Proof study

Demewoz HaileKassandra L. HardingSusan A. McLaughlinCharlie AshbaughVanessa Garcia15
Nature Medicine
2025
2025/6/30
00 p.1-11
Previous research suggests detrimental health effects associated with consuming processed foods, including processed meats, sugar-sweetened beverages (SSBs) and trans fatty acids (TFAs). However, systematic characterization of the dose–response relationships between these foods and health outcomes i...
Cancer preventionDiabetesRisk factorsVascular diseases
10.1038/S41591-025-03775-8
ISSN:1078-8956

Health effects associated with smoking: a Burden of Proof study

Dai XiaochenGil Gabriela F.Reitsma Marissa B.Ahmad Noah S.Anderson Jason A.26
Nature Medicine
2022
2022/10/10
Vol.28 No.10 p.2045-2055
As a leading behavioral risk factor for numerous health outcomes, smoking is a major ongoing public health challenge. Although evidence on the health effects of smoking has been widely reported, few attempts have evaluated the dose–response relationship between smoking and a diverse range of health ...
CancerRisk factors
10.1038/S41591-022-01978-X
ISSN:1078-8956

Health effects associated with chewing tobacco: a Burden of Proof study

Gabriela F. GilJason A. AndersonAleksandr AravkinKayleigh BhangdiaSinclair Carr18
Nature Communications
2024
2024/2/5
Vol.15 No.1 p.1-17
Chewing tobacco use poses serious health risks; yet it has not received as much attention as other tobacco-related products. This study synthesizes existing evidence regarding the health impacts of chewing tobacco while accounting for various sources of uncertainty. We conducted a systematic re...
DiseasesMedical researchRisk factors
10.1038/S41467-024-45074-9
ISSN:2041-1723

Health effects associated with vegetable consumption: a Burden of Proof study

Stanaway Jeffrey D.Afshin AshkanAshbaugh CharlieBisignano CatherineBrauer Michael19
Nature Medicine
2022
2022/10/10
Vol.28 No.10 p.2066-2074
Previous research suggests a protective effect of vegetable consumption against chronic disease, but the quality of evidence underlying those findings remains uncertain. We applied a Bayesian meta-regression tool to estimate the mean risk function and quantify the quality of evidence for association...
CancerCardiovascular diseasesRisk factors
10.1038/S41591-022-01970-5
ISSN:1078-8956

Health effects associated with alcohol consumption: a Burden of Proof study

Xiaochen DaiSneha I. NicholsonHilary R. LawlorSinclair CarrJaimie D. Steinmetz17
Nature Health
2026
2026/6/1
00 p.1-21
The relationship between alcohol and health is complex, and the evidence relating alcohol consumption to various cardiovascular diseases, cancers and other conditions is evolving. Moreover, alcohol drinking guidelines vary widely. Here we conducted 16 systematic reviews across four databases and con...
DiseasesRisk factors
10.1038/S44360-026-00139-5
ISSN:3005-0693